The same is true for pottery. sun jialing's public prezis go to profile page ›. Paired samples t-test and Wilcoxon signed-rank test were used to compare clinical data pre- and post-treatment. However, in Ishak stable patients, qFibrosis revealed hitherto undetected changes, allowing for further subcategorization into regression (There is compelling evidence that liver fibrosis and even cirrhosis can be reversed after suppression of hepatitis B virus (HBV)The gold standard for evaluation of liver fibrosis improvement is still the liver biopsyRecently, qFibrosis, a stain-free and fully automated approach based on second harmonic generation/two-photon excitation fluorescence (SHG/TPEF) microscopy has been developedA total of 183 patients with paired liver biopsies were enrolled. Get the most important science stories of the day, free in your inbox. Wanless, I. R., Nakashima, E. & Sherman, M. Regression of human cirrhosis.

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Unmethylated cytosine-phosphate-guanosine (CpG) oligodeoxynucleotides are immunostimulatory nucleic acids wildly utilized as adjuvants or for vaccines to treat diseases. This study was funded by National Science and Technology Major Project (2013ZX10002004), National Key Technologies R&D Program (2015BAI13B09), Key Project from Beijing Municipal Science and Technology Commission (D161100002716003) and National Natural Science Foundation of China (81670539).Liver Research Center, Beijing Key Laboratory of Translational Medicine in Liver Cirrhosis, National Clinical Research Center for Digestive Disease, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, ChinaYameng Sun, Jialing Zhou, Xiaoning Wu, Xiaojuan Ou, Jidong Jia & Hong YouDepartment of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, ChinaInfectious Disease Department, Affiliated Hospital of Yanbian University, Yanji, 133000, ChinaDepartment of Gastroenterology and Hepatology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, ChinaDepartment of Gastroenterology and Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, 100069, ChinaDepartment of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, 050051, ChinaDepartment of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, 200032, ChinaPathology Department, China-Japan Friendship Hospital, Beijing, 100029, ChinaPathology Department, Beijing Youan Hospital, Capital Medical University, Beijing, 100069, ChinaDepartment of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, National University Hospital, Singapore, 119074, SingaporeDepartment of Pathology, New York University School of Medicine, New York, NY, 10016, USAYou can also search for this author in You are using a browser version with limited support for CSS. Studies were registered at ClinicalTrials.gov (registration number NCT01938781, NCT01938820).Liver biopsy specimens were routinely processed. & Afdhal, N. H. Progression of fibrosis in advanced chronic hepatitis C: evaluation by morphometric image analysis. Bedossa, P. & Poynard, T. An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group. Bekijk het profiel van Jialing Sun op LinkedIn, de grootste professionele community ter wereld. The BH3-only protein BAD mediates TNFα cytotoxicity despite concurrent activation of IKK and NF-κB in septic shock. You can also search for this author in First, fibrosis regression may improve liver-related clinical endpoints such as portal hypertension, hepatic decompensation and hepatocellular carcinomaIn conclusion, qFibrosis can sensitively reflect fine histological fibrosis changes and detect fibrosis improvements.

and JavaScript.Current widely used semiquantitative histological assessment methods are insensitive to identify subtle changes of liver fibrosis.

One-way ANOVA and Kruskal-Wallis test were used to assess the changes of LSM and collagen percentage area (CPA) in specific conditions. Formalin-fixed, paraffin-embedded, 5 µm thick histological sections were stained with hematoxylin and eosin (H&E), Masson Trichrome and ReticulinAll liver biopsy specimens were imaged by Genesis200The sophisticated image analysis algorithms extracted 100 collagen features from SHG images. Theise consults for and received grants from Histoindex. She obtained a postgraduate degree from Department of Ceramic Design of Academy of Arts & Design, Tsinghua University. SUN Jialing was born in Qingdao, China.

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