7 entries. Function i. Tityus obscurus is the main scorpion responsible for accidents in the Amazon region.. Tityus obscurus, similar to T. serrulatus venom, exerted edematogenic activity in mice. Dr. Vital Brasil, 1500, 05503-900, São Paulo, SP, Brazil and Post-Graduation Program in Zoology, Institute of Biosciences, University of São Paulo, Av. Laboratory of Bioprospection, Faculty of Health Sciences, University of Brasilia, Brasilia, BrazilLaboratory of Neuropharmacology, Institute of Biological Sciences, University of Brasilia, Brasilia, BrazilLaboratory of Bioactive Compounds and Nanobiotechnology, Faculty of Ceilandia, University of Brasilia, Brasilia, BrazilLaboratory of Bioactive Compounds and Nanobiotechnology, Faculty of Ceilandia, University of Brasilia, Brasilia, BrazilLaboratory of Bioprospection, Faculty of Health Sciences, University of Brasilia, Brasilia, BrazilLaboratory of Neuropharmacology, Institute of Biological Sciences, University of Brasilia, Brasilia, BrazilLaboratory of Bioprospection, Faculty of Health Sciences, University of Brasilia, Brasilia, BrazilLaboratory of Neuropharmacology, Institute of Biological Sciences, University of Brasilia, Brasilia, BrazilLaboratory of Bioactive Compounds and Nanobiotechnology, Faculty of Ceilandia, University of Brasilia, Brasilia, BrazilLaboratory of Bioactive Compounds and Nanobiotechnology, Faculty of Ceilandia, University of Brasilia, Brasilia, BrazilLaboratory of Bioprospection, Faculty of Health Sciences, University of Brasilia, Brasilia, BrazilLaboratory of Neuropharmacology, Institute of Biological Sciences, University of Brasilia, Brasilia, BrazilUse the link below to share a full-text version of this article with your friends and colleagues. Tityus obscurus venom caused hemorrhagic patches in the lung of rats.. ScienceDirect ® is a registered trademark of Elsevier B.V.ScienceDirect ® is a registered trademark of Elsevier B.V. Tityus bahiensis (Brazilian scorpion) SCX1_TITBA Toxin Tb1 (PT-Mice-beta* NaTx6.2) (Tb … and you may need to create a new Wiley Online Library account.Enter your email address below and we will send you your usernameIf the address matches an existing account you will receive an email with instructions to retrieve your username

Juveniles can be sexed by checking the exuvia for dilated basal middle lamellae (see Fig 6), indicating the females (3). Prof. Lineu Prestes, 2415, 05508-900, São Paulo, SP, Brazil.Present address: Laboratory of Pain and Signaling, Butantan Institute, São Paulo, Brazil, Butantan Institute and Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, Av.

Both nociceptive and lethal activities of T. obscurus venom were lower than those caused by T. serrulatus venom in mice.

The most frequent species involved in human stings are referred as being T. obscurus, Tityus silvestris, and T. metuendus 5),(7, probably owing to their large geographical distribution in the Amazon basin; whereas Tityus apiacas Lourenço, 2002, has a Southern distribution in Amazonia, South of the Rio Solimões/Amazonas in the States of Amazonas, Mato Grosso and Pará, Brazil.

Significance: The scorpion Tityus obscurus causes many envenoming accidents of medical importance in Brazilian Amazon region; despite to this, very few is known about the toxinology of this animal. If you do not receive an email within 10 minutes, your email address may not be registered, Tityus asthenes (Pocock, 1893) by ... but this is less marked than in T.obscurus (2). Prof. Lineu Prestes, 2415, 05508-900, São Paulo, SP, Brazil.Present address: Biotechnology Center, Nuclear and Energy Research Institute (IPEN/CNEN-SP), Av. Reviewed-Annotation score: -Experimental evidence at protein level i. In 1970, Bartholomew et al. New drugs are constantly in demand, and nature's biodiversity is a rich source of new compounds for therapeutic applications. The diagnosis of pancreatitis was based only on the dosage of serum amylase. 4), also known as T. cambridgei or T. paraensis, is the most dangerous found in the Amazon forest and it is responsible for … Prof. Lineu Prestes, 2242, 05508-000, São Paulo, SP, Brazil.We use cookies to help provide and enhance our service and tailor content and ads. Synthetic peptides based on the transcriptome analysis of scorpion venoms of Online Version of Record before inclusion in an issuePlease check your email for instructions on resetting your password. Tityus: Species: serrulatus: Venom protein entries in UniProtKB/Swiss-Prot 180 entries grouped by species (browse by taxonomy, browse by keywords) reorder by family. [4] reported 24 cases of acute pancreatitis which appeared soon after Tityus trinitatis sting. The Tityus obscurus scorpion‐derived synthetic peptide (FFGTLFKLGSKLIPGVMKLFSKKKER), in concentrations ranging from 6.24 to 0.39 μM, proved to be the most active one against simian immunodeficiency virus (SIV) replication in the HUT‐78 cell line and in primary human leukocytes, with the lowest toxicity for these cells.

In the Brazilian Amazonian region scorpion stings are a common event caused by Tityus obscurus. There are a great number of studies about Brazilian scorpions. I have read and accept the Wiley Online Library Terms and Conditions of Use

The main objective of this work was to perform the molecular cloning of the putative Na+-channel scorpion toxins (NaScTxs) from T. pachyurus and T. obscurus venom glands and to analyze their phylogenetic relationship with other known NaScTxs from Tityus species. Affects sodium-permeability in pituitary GH3 cells in culture.

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